Jack Clarke returns to the starting line-up as Mike Dodds makes three changes from Monday’s defeat against Blackburn in the Sky Bet Championship.
The 23-year-old starts for the first time since picking up an injury against Birmingham in February, with the winger looking to add to his 15 league goals this campaign.
Chris Rigg and Leo Hjelde claim spots in the starting XI, with Patrick Roberts and Callum Styles both moving to the bench.
Long-term absentees Niall Huggins, Dennis Cirkin, Jenson Seelt, Elliot Embleton, and Nazariy Rusyn all remain in the treatment room for a while longer.
SAFC XI: Patterson, Hume, Ballard, O’Nien ©, Hjelde, Ekwah, Neil, Rigg, Aouchiche, Clarke, Jobe.
Substitutes: Bishop, Pembélé, Luís Hemir, Burstow, Mundle, Styles, Alese, Dack, Roberts.