Black Cats exit the FA Cup at the KC Stadium.
Sunderland were denied a return trip to Wembley as three second-half goals saw Hull to victory at the KC Stadium in the quarter-finals of the FA Cup with Budweiser.
A fine first-half penalty save from Oscar Ustari ensured the game was goalless at the break, but the Tigers found a way through 22 minutes from time via Curtis Davies' header from a set piece.
David Meyler and Matty Fryatt added further goals as Hull secured their place in the final four of the competition.
Sunderland had been boosted by Ustari's fine spot-kick save on Sone Aluko but couldn't push on and secure a return trip to the national stadium following the Capital One Cup final defeat to Manchester City.
The Black Cats' starting side showed six changes from the team which started the game against City in the Wearsiders' last outing, with Steven Fletcher and Ignacio Scocco getting the nod in attack.
Meanwhile Andrea Dossena, Emanuele Giaccherini and Santiago Vergini also came in, with Ustari taking over from Vito Mannone in goal.
Adam Johnson, Ki Sung-Yueng and Fabio Borini all joined Mannone in dropping to the bench, with Wes Brown and Marcos Alonso missing out.
Former Black Cats Meyler and Ahmed Elmohamady both started for City, who got off on the front foot and rattled the woodwork after only four minutes when Maynor Figueroa's cross struck the top of Ustari's crossbar.
Sunderland took time to settle but pieced a couple of neat moves together once they did, with Scocco firing an 18th-minute opportunity over the bar from 12 yards after Phil Bardsley latched onto a Giaccherini backheel and fired in a cross from the right.
Fryatt flicked a header just wide with the half-hour approaching and the hosts had a golden chance to pull ahead 10 minutes before the break - winning a penalty after Seb Larsson was adjudged to have fouled Aluko on the turn.
Aluko took the spot-kick himself only for Ustari to make a superb save away to his right, guessing correctly to stop the shot before quickly pouncing on the loose ball.
There was still time for chances at either end before the break, with Giaccherini curling an effort just wide before Ustari did well again to tip Liam Rosenior's powerful drive away for a corner.
After an frenetic end to the first half, the start to the second period was low-key with Ustari only called into action once – grabbing Aluko's cross ahead of the challenging Fryatt.
Meanwhile Scocco saw a low drive from the left-hand edge of the box saved by McGregor before he was replaced along with Giaccherini as Adam Johnson and Fabio Borini entered the fray with 24 minutes to go.
But Hull responded by taking the lead soon afterwards when a free-kick from the right was met firmly by Davies, whose header found the far corner.
The Tigers hit the visitors with a quick one-two punch as Meyler beat Cattermole to a 50-50 ball on half-way and advanced before slotting beyond an exposed Ustari.
And the hosts sealed a semi-final spot when Cattermole's back-pass was intercepted by Fryatt, who steered a low shot into the back of the net 13 minutes from the end.
Meyler fizzed a powerful drive just over late on as City booked their place in the last four and denied Sunderland a quick return to Wembley.
And so the Black Cats' run in the cups comes to an end, with attention now solely focused on the final 12 matches of the Barclays Premier League campaign.
- Yellow Huddlestone
- Elmohamady (Quinn)
- Sagbo (Boyd)
- Aluko (Koren)
- Cattermole Yellow
- Scocco (Borini) Yellow
- Giaccherini (Johnson)